Are you taking too much vitamin D?

frank shallenberger md

“Vitamin D is dangerous.” “You have to be very careful with vitamin D.” “Vitamin D can easily become toxic and lead to many problems.” “It is risky to take more than 1,000 units of vitamin D per day.” Have you ever heard statements like these? I have. Probably a month doesn’t go by before I find out that some doctor said as much when he found out I had prescribed a “dangerously high dose of vitamin D.” So imagine how happy I was to find a review article on the incredible safety of vitamin D in one of the most respected medical journals in the U.S.

In the May 2015 edition of the Mayo Clinic Proceedings, researchers reported on a study that looked at over 20,000 vitamin D blood tests done between 2002 and 2011. They found that the number of people testing with vitamin D levels over 50 ng/ml increased more than 25 times. No doubt this was because of the fact that vitamin D supplementation has been shown to be one of the most important things we can do for our health. And more and more doctors are prescribing it. But what about safety? If the levels of vitamin D increased so dramatically over that period of time, surely the number of toxicity cases went up as well? Not so fast, Pardner.

Out of more than 20,000 cases, they found only one case of toxicity. And that patient had a vitamin D blood level of 364 ng/ml! This is more than five times higher than the recommended optimum blood level of 70 ng/ml. The other concern that doctors have is the chance of harmful elevated calcium levels. This happened only in four patients. And when their vitamin D intake was reduced, the calcium levels quickly returned to normal. All those concerns of kidney stones, cardiovascular calcifications, and death did not occur in one person – even in the patient with the 364 ng/ml level. And this isn’t the only study verifying the incredible safety of vitamin D even in high doses. Another study reported just last year on more than 17,000 healthy adult volunteers who were taking doses of vitamin D up to 20,000 units a day. Not one of them had any toxicity.  

Michael L. Holick, MD is an endocrinologist and is probably the world’s leading expert on vitamin D supplementation. Here’s what he had to say about vitamin D in the same Mayo Clinic Journal issue.

“There is no credible scientific literature suggesting that vitamin D intake increases the risk for kidney stones. Similarly, data are weak regarding the association between vitamin D intake and cardiovascular calcifications. To the contrary, current evidence suggests that improvement in vitamin D status reduces the risk for hypertension, stroke, and myocardial infarction. The evidence is clear that vitamin D toxicity is one of the rarest medical conditions and is typically due to intentional or inadvertent intake of extremely high doses of vitamin D, usually in the range of more than 50,000-100,000 units a day for months to years.”

So there you have it. I hope this puts the vitamin D toxicity crisis in its proper place. It’s always amazing to me when a doctor who spends 80% of his life writing prescriptions for patent drugs with serious documented toxicity gets his dander up over a patient taking a vitamin. So if your doctor ever gets excited over your vitamin D intake, be sure to help him out and give him these references so he can sleep better.

In the meantime be sure to take enough vitamin D to get your blood levels between 50-70 ng/ml. This is the level that offers maximum protection. I usually recommend 5,000 IU daily of vitamin D to get to that level. And once you get to that level, check your blood calcium just to make sure that you aren’t that exceedingly rare person whose levels go up from taking the vitamin.

REF: Dudenkov DV, Yawn BP, et al. Changing Incidence of Serum 25-Hydroxyvitamin D Values Above 50 ng/mL: A 10-Year Population-Based Study. Mayo Clin Proc. 2015 May;90(5):577-86.
Holick MF.  Vitamin D Is Not as Toxic as Was Once Thought: A Historical and an Up-to-Date Perspective. Mayo Clin Proc. 2015 May;90(5):561-4.

Yours for better health,

By Dr. Frank Shallenberger, MD

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Prolozone May Cure The Cause Of Your Pain

frank shallenberger md

Last December, I had the privilege of traveling to India again. If you’ve read any of my previous stories about my journeys to this impoverished nation, you know some of the medical miracles I’ve seen there from the innovative treatments I brought them. This trip was no different. In fact, I saw some of the most devastating pain cases resolved in minutes.

The journey first took us through Ludhiana, India, where My wife and I stayed with Dr. S. Sibia. Dr. Sibia told us why we see so many miracles in India. “We are looking for the cheapest way to get the greatest result. In America, the system is geared toward getting the most expensive treatment regardless of the outcome.” He’s right! And he also was right about something else: He predicted that the charitable hospital we volunteer at would soak up our ozone therapy like a sponge. The doctors, indeed, soaked it up.

So we began to treat a few patients with ozone. What began as a slow trickle of patients quickly turned into a torrent, especially after what the staff saw exceeded their expectations.

We started in the orthopedic department. Our first patient was an older man with degenerated knees. In two minutes, he got off the table nearly free of pain after an injection of medical ozone.

(This is the Prolozone therapy I’ve discussed in the past. My good friend and colleague, Frank Shallenberger, MD, editor of Real Cures newsletter, termed it “Prolozone” when he combined the words “prolotherapy” and “ozone.”)

The second patient limped in with severe arthritis in his left hip. In minutes, he was at least 50% improved. Several more patients with knee degeneration arrived. We saw the same results — in almost all knee cases — nearly total elimination of pain.

Shocked at what he was seeing, the orthopedic doctor brought us a woman with a frozen shoulder. It froze up soon after she had a chest infection the doctor had drained with a tube through her chest. The first part of the treatment was to inject the scar on her chest with a local anesthetic (neural therapy). Her shoulder freed up about 50%. Then we put ozone into her shoulder and her motion increased yet further.

Then the eye doctor brought us a case of a degenerating (pigment layer) retina. A picture showed significant leakage of a fluorescent dye within her retina. And, she was scared of anything new. But her loss of vision scared her worse. She rolled up her sleeve for intravenous ozone therapy. Two days later, a retina specialist re-photographed her eye and showed a 40% reduction in leakage. Needless to say, she tracked us down in the hospital most of our remaining days for further treatment until her ophthalmologist himself was ready to do it.

On the third day, the doctors wheeled a young man (27) into the treatment room with a severely prolapsed disc. He could not stand upright, bent over at about 20º. His pain, radiating from his hip and down his leg, was so severe he needed assistance to rise out of the wheelchair. He could not lie flat on his abdomen. For this reason, he’s one of the few patients that the treatment itself was highly painful.

I’ve found that injecting Prolozone into the lumbar facet and sacroiliac joints helped most of my back patients with or without disc problems.

Unlike the knee cases, he was not better immediately after the injection. The knee cases were dramatically better nearly instantly. I told the doctor that this was one case I suspected would take at least 30 minutes. We were injecting the gas distant from the disc. It would take time for it to migrate to the affected area. So they sent the patient back to the ward.

Thirty minutes later, we checked up on him. He was standing up straight! By the end of the day, not only was he getting out of bed upright without assistance, he could bend over. By morning he told us the pain was 95% relieved! He was left with very limited pain in his back.

Word of this spread rapidly around the hospital. As many people in the hospital came to see. Even some of the doctors came for treatment. They brought their parents, children, and spouses into wherever we were working, hoping to squeeze in a treatment (especially for knees). The results were just like all the others. It was wonderful!

You might wonder how and why these results could be so dramatic, so fast, and last so long. The cause of pain is inflammation. Inflammation is a self-perpetuating cycle of damage. This limits oxygen, which further induces damage and limits the body’s ability to repair. So we administered a gas that’s 99% oxygen and 1% ozone. The instillation of oxygen provides instant energy production in the oxygen-starved cells. Ozone stimulates powerful chemical mediators of repair, regeneration, and modulation of inflammation.

If you would like to find a Prolozone therapist, please visit You can find out more about its more widely known cousin, prolotherapy, at

One final note: We would like to extend a heartfelt thanks to Longevity Resources Company ( and its CEO Roger Chown. They most graciously donated the ozone machine to the hospital.

Longevity also makes EWOT systems for those interested in reversing aging.

By Dr. Frank Shallenberger, MD

For more information about the Dr. Frank Shallenberger MD and the Second Opinion Newsletter Click Here!